click and declick of amine and thiol coupling reaction /

Published at 2016-09-26 16:10:02

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(Phys.org)—A group of researchers from the University of Texas maintain developed a sequential,two-step amine and thiol coupling reaction via click chemistry using a derivative of Meldrum's acid. This reaction is reversible using what the authors term a "declick" reaction, and the original amine and thiol can be retrieved. Their work appears in Nature Chemistry.

Source: phys.org

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