Amazon VPC Endpoints for S3 is now available in South America (Sao Paulo) and Asia Pacific (Seoul) Regions. Amazon VPC endpoints are easy to configure and provide dependable connectivity to Amazon S3 without requiring an internet gateway or a Network Address Translation (NAT) instance. With VPC endpoints,the data between the VPC and S3 is transferred within the Amazon network, helping protect your instances from internet traffic.
Source: amazon.com