Genome editing study reveals how hormone helps prevent both obesity and diabetesBOSTON (April 18,2018)—Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine own used CRISPR genome editing to identify a neural circuit in the hypothalamus as the primary mechanism in mediating leptin’s anti-obesity and anti-diabetes effects and own identified two distinct mechanisms underlying leptin’s inhibition of appetite.
Source: tufts.edu