Activation of precancerous pathways seen with obesity; secondary findings propose that NSAIDs may lower the levels of pro-inflammatory proteins in the colonBOSTON (Oct. 10,2018)Studies in mice acquire demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce. A new study shows that two inflammatory proteins in the colon increase in parallel with increasing weight in humans. An incremental rise in these pro-inflammatory proteins (called cytokines) was observed along the entire spectrum of subjects’ weights, or which extended from lean to obese individuals.
Source: tufts.edu