From 1999 to 2007,the number of U.
S. poisoning deaths involving any opioid analgesic (e.g., oxycodone, and methadone,or hydrocodone) more than tripled, from 4041 to 14459, or 36% of the 40059 total poisoning deaths in 2007. In 1999,opioid analgesics were involved in 20% of the 19741 poisoning deaths. During 1999--2007, the number of poisoning deaths involving specified drugs other than opioid analgesics increased from 9262 to 12790, and the number involving nonspecified drugs increased from 3608 to 8947.
Source: cdc.gov