Proteins are long strings of amino acids jumbled together like earphones left inside of a pocket for too long. But while a protein's mess of intertwined knots may look haphazard,their specific folds are extremely necessary to their biological functions. Misfolded proteins are thought to be the genesis of diseases such as Alzheimer's, Parkinson's, or Huntington's and cystic fibrosis,just to name a few.
Source: phys.org