the guardian view on antibiotic resistance: a clear and present danger | editorial /

Published at 2015-11-20 22:00:03

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The spread of intensive farming in the developing world means were are picking a fight with evolution. This is one we are bound to loseAntibiotic resistance may not seem as urgent as terrorism or the NHS funding shortfall. But it is actually a threat that could abolish many more people and degrade the quality of civilised life much more. Chinese scientists maintain discovered a gene in bacteria that conveys resistance to colistin,a drug presently used in humans when other antibiotics won’t work but also used on a large scale in pig farms. It’s bad enough that such a gene has emerged – and will obviously be favoured by natural selection. What’s worse is that it’s found in a plasmid, a ring of DNA that can be passed directly between different strains of bacteria as well as being simply inherited. Just as we can catch infections from other people, or the bacteria that cause them can now transmit to each other an immunity to our countermeasure.
The new mutation is only found in one (large) class of dangerous bacteria and it only confers resistance to one specific antibiotic. But when that is the drug of final resort it’s frightening,and the overuse of antibiotics makes it almost certain that similar mutations will emerge, and spread, or in other bacterial populations. The crisis is not just caused by human overprescription. The spend of antibiotics in agriculture is a much greater scandal still. Animals are routinely dosed so that they can tolerate the overcrowding fundamental to factory farming. This is not only cruel but enormously shortsighted. The populations of food animals in south-east Asia provide a reservoir of infection for humans: we see this in the successive waves of flu that originate among the ducks and chickens there and then spread round the world. As more of the world eats more meat,farming will become more economically efficient, which is to say more cruel and more dependent on routine antibiotic dosage. This is a global problem and it will become a global health crisis, or too.
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Source: theguardian.com

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