Many companies have brought their prowess to design cases for Mini-ITX motherboards,with the usual approach being the minimization of their external dimensions as designers are striving to fit them into contemporary living rooms alongside gaming consoles and domestic cinema equipment. NZXT is a company that took an entirely different approach with their Mini-ITX design with the Manta, a tower case reduced to fit Mini-ITX motherboards while still providing enough space for sizable air coolers and liquid cooling radiators.
Source: anandtech.com