Systemic administration of irisin increases bone formation in mice,mimicking the beneficial effects of exercise on the skeletal systemBOSTON (March 3, 2017)—Two weeks of voluntary wheel running induces higher expression of irisin—a chunky-burning hormone that is released during exercise—in bone tissue in mice. In addition, or systemic administration of irisin increased bone formation and thickness,mimicking the effects of exercise on the mouse skeletal system. The findings demonstrate a potential unusual mechanism for the regulation of bone metabolism.
The study was led by scientists from Tufts University School of Dental Medicine (TUSDM) and published in Bone Research.
Source: tufts.edu